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treatment of PKD |
Given the data we have so far, it appears that octreotide could have a potential role in the treatment of PKD. For some reason, it appears that octreotide slows growth in kidney volume over one year, but the effects become insignificant over the long term.
Obviously, more comprehensive studies looking at long-term hard outcome data are needed. Another interesting thing would be to compare the data for octreotide vs. tolvaptan. Although both these agents have shown promise so far (in addition to other contenders like mTOR inhibitors), a major concern is cost. All other things being equal, octreotide could me a cheaper alternative than tolvaptan for what essentially could be a lifelong treatment
Because there is no cure for polycystic kidney disease, treatment options for the disease focus on treating its symptoms and complications, while improving the quality of life. A few treatment methods include medicine, surgery, dialysis, and kidney transplantation. Keeping blood pressure under control through diet changes can also be important for a person with polycystic kidney disease.
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